ACRBP_HUMAN - dbPTM
ACRBP_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ACRBP_HUMAN
UniProt AC Q8NEB7
Protein Name Acrosin-binding protein
Gene Name ACRBP {ECO:0000312|EMBL:AAH33010.1}
Organism Homo sapiens (Human).
Sequence Length 543
Subcellular Localization Secreted . Cytoplasmic vesicle, secretory vesicle, acrosome .
Protein Description May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin..
Protein Sequence MRKPAAGFLPSLLKVLLLPLAPAAAQDSTQASTPGSPLSPTEYERFFALLTPTWKAETTCRLRATHGCRNPTLVQLDQYENHGLVPDGAVCSNLPYASWFESFCQFTHYRCSNHVYYAKRVLCSQPVSILSPNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEIDEMNEIYDENSYWRNQNPGSLLQLPHTEALLVLCYSIVENTCIITPTAKAWKYMEEEILGFGKSVCDSLGRRHMSTCALCDFCSLKLEQCHSEASLQRQQCDTSHKTPFVSPLLASQSLSIGNQVGSPESGRFYGLDLYGGLHMDFWCARLATKGCEDVRVSGWLQTEFLSFQDGDFPTKICDTDYIQYPNYCSFKSQQCLMRNRNRKVSRMRCLQNETYSALSPGKSEDVVLRWSQEFSTLTLGQFG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
11PhosphorylationPAAGFLPSLLKVLLL
CCCCCHHHHHHHHHH		48.7824719451
128PhosphorylationVLCSQPVSILSPNTL
EHHCCCEEECCCCHH		25.2125693802
141PhosphorylationTLKEIEASAEVSPTT
HHHHHHHCCCCCCCC		16.5122252499
145PhosphorylationIEASAEVSPTTMTSP
HHHCCCCCCCCCCCC		14.1822252507
260PhosphorylationEPKFHSESLSSNPSS
CCCCCCHHHCCCCCC		36.2428961369
277PhosphorylationPRVREVESTPMIMEN
CCCEECCCCHHHHHH		42.8824275569
291PhosphorylationNIQELIRSAQEIDEM
HHHHHHHHHHHHHHH		27.5830622161
302PhosphorylationIDEMNEIYDENSYWR
HHHHHHHCCCCCCCC		15.8330622161
347AcetylationTPTAKAWKYMEEEIL
CCCHHHHHHHHHHHH		39.3125038526
370PhosphorylationSLGRRHMSTCALCDF
HHCCHHCCHHHHHHH		17.7625693802
371PhosphorylationLGRRHMSTCALCDFC
HCCHHCCHHHHHHHH		8.3325693802
381AcetylationLCDFCSLKLEQCHSE
HHHHHHCCHHHHCCH		33.4125038526
387PhosphorylationLKLEQCHSEASLQRQ
CCHHHHCCHHHHHHH		42.3530622161
390PhosphorylationEQCHSEASLQRQQCD
HHHCCHHHHHHHHCC		22.4530622161
402PhosphorylationQCDTSHKTPFVSPLL
HCCCCCCCCCCHHHH		19.2825693802
406PhosphorylationSHKTPFVSPLLASQS
CCCCCCCHHHHHCCC		15.3725693802
411PhosphorylationFVSPLLASQSLSIGN
CCHHHHHCCCCCCCC		21.9225693802
413PhosphorylationSPLLASQSLSIGNQV
HHHHHCCCCCCCCCC		22.9125693802
415PhosphorylationLLASQSLSIGNQVGS
HHHCCCCCCCCCCCC		33.4325693802
491AcetylationYPNYCSFKSQQCLMR
CCCCCCHHHHHHHHH		30.9425038526
519PhosphorylationNETYSALSPGKSEDV
CCCCCCCCCCCCHHH		31.1824719451
523PhosphorylationSALSPGKSEDVVLRW
CCCCCCCCHHHHHEE		44.9722210691
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ACRBP_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ACRBP_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ACRBP_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ACRBP_HUMAN !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ACRBP_HUMAN

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Related Literatures of Post-Translational Modification

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