ACOT9_MOUSE - dbPTM
ACOT9_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ACOT9_MOUSE
UniProt AC Q9R0X4
Protein Name Acyl-coenzyme A thioesterase 9, mitochondrial
Gene Name Acot9
Organism Mus musculus (Mouse).
Sequence Length 439
Subcellular Localization Mitochondrion .
Protein Description Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs..
Protein Sequence MKRAAIRLWTLNKGLLTHGRGLSQGSQYKISEPLHIHQVRDKLREIVGVSTVWRDHVKAMEERKLLHSFLPKSQKVLPPRKMRDSYIEVLLPLGTDPELRDKYVTVQNTVRFGRILEDLDSLGVLVCYMHNHNHSTKMSPLSIVTVLVDKIDMCKHSLSPEQDIKFTGHVSWVGNTSMEVKMKMFQLHNDEKYWPVLDATFVMVARDSENKGPAFVNPLIPENKEEEELFKQGELNKSRRIAFSTSSLLKVAPSSEERNIIHELFLTTLDPKTISFQSRILPPKAVWMEDTKLKSLDICHPQERNVFNRIFGGFLMRKAYELAWATACSFGGSRPYVVTVDDIMFQKPVEVGSLLFLSSQVCFTQDNYIQVRVHSEVSSLDSREHMTTNVFHFTFMSEKEVPLIFPKTYGESMLYLDGQRHFKSMSTPVTLKKDYPVEP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
85PhosphorylationPPRKMRDSYIEVLLP
CCHHCCCCEEEEEEE		20.0421454597
86PhosphorylationPRKMRDSYIEVLLPL
CHHCCCCEEEEEEEC		12.8521454597
95PhosphorylationEVLLPLGTDPELRDK
EEEEECCCCHHHHHC		56.9421454597
102AcetylationTDPELRDKYVTVQNT
CCHHHHHCEEEEECC		34.8822646759
145PhosphorylationMSPLSIVTVLVDKID
CCCHHHEEEEHHHHC		13.3751457915
157PhosphorylationKIDMCKHSLSPEQDI
HHCCCCCCCCHHHCE		18.94-
159PhosphorylationDMCKHSLSPEQDIKF
CCCCCCCCHHHCEEE		29.4354885837
224AcetylationNPLIPENKEEEELFK
CCCCCCCHHHHHHHH		65.9123954790
231AcetylationKEEEELFKQGELNKS
HHHHHHHHHCCCCHH		70.7623236377
244PhosphorylationKSRRIAFSTSSLLKV
HHHHEEEEHHHHCCC		20.5427180971
245PhosphorylationSRRIAFSTSSLLKVA
HHHEEEEHHHHCCCC		18.8428833060
246PhosphorylationRRIAFSTSSLLKVAP
HHEEEEHHHHCCCCC		20.1428833060
247PhosphorylationRIAFSTSSLLKVAPS
HEEEEHHHHCCCCCC		37.5028833060
254PhosphorylationSLLKVAPSSEERNII
HHCCCCCCHHHHCHH		40.4129899451
255PhosphorylationLLKVAPSSEERNIIH
HCCCCCCHHHHCHHH		42.2825195567
273PhosphorylationLTTLDPKTISFQSRI
HHCCCCCCEEECCCC		27.5219060867
364PhosphorylationLSSQVCFTQDNYIQV
EEEEEEECCCCEEEE		29.8625338131
382PhosphorylationSEVSSLDSREHMTTN
EECCCCCCCCCEECC		44.8836520413
423AcetylationLDGQRHFKSMSTPVT
ECCCCCCCCCCCCCE		38.842395315
427PhosphorylationRHFKSMSTPVTLKKD
CCCCCCCCCCEECCC		17.0923737553
430PhosphorylationKSMSTPVTLKKDYPV
CCCCCCCEECCCCCC		33.78-
432AcetylationMSTPVTLKKDYPVEP
CCCCCEECCCCCCCC		33.942413461
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ACOT9_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ACOT9_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ACOT9_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ACOT9_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ACOT9_MOUSE

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Related Literatures of Post-Translational Modification

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