ACO1_ARATH - dbPTM
ACO1_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ACO1_ARATH
UniProt AC Q42560
Protein Name Aconitate hydratase 1 {ECO:0000303|PubMed:25061985}
Gene Name ACO1 {ECO:0000303|PubMed:25061985}
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 898
Subcellular Localization Cytoplasm . Mitochondrion .
Protein Description Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. Contributes to oxidative stress tolerance. [PubMed: 17013749 May have a role in respiration]
Protein Sequence MASENPFRSILKALEKPDGGEFGNYYSLPALNDPRIDKLPYSIRILLESAIRNCDEFQVKSKDVEKILDWENTSPKQVEIPFKPARVLLQDFTGVPAVVDLACMRDAMNNLGGDSNKINPLVPVDLVIDHSVQVDVARSENAVQANMELEFQRNKERFAFLKWGSNAFHNMLVVPPGSGIVHQVNLEYLARVVFNTNGLLYPDSVVGTDSHTTMIDGLGVAGWGVGGIEAEATMLGQPMSMVLPGVVGFKLTGKLRDGMTATDLVLTVTQMLRKHGVVGKFVEFHGEGMRELSLADRATIANMSPEYGATMGFFPVDHVTLQYLRLTGRSDDTVSMIEAYLRANKMFVDYSEPESKTVYSSCLELNLEDVEPCVSGPKRPHDRVPLKEMKADWHSCLDNRVGFKGFAVPKEAQSKAVEFNFNGTTAQLRHGDVVIAAITSCTNTSNPSVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVTKYLAKSGLQKYLNQLGFSIVGYGCTTCIGNSGDIHEAVASAIVDNDLVASAVLSGNRNFEGRVHPLTRANYLASPPLVVAYALAGTVDIDFETQPIGTGKDGKQIFFRDIWPSNKEVAEVVQSSVLPDMFKATYEAITKGNSMWNQLSVASGTLYEWDPKSTYIHEPPYFKGMTMSPPGPHGVKDAYCLLNFGDSITTDHISPAGSIHKDSPAAKYLMERGVDRRDFNSYGSRRGNDEIMARGTFANIRIVNKHLKGEVGPKTVHIPTGEKLSVFDAAMKYRNEGRDTIILAGAEYGSGSSRDWAAKGPMLLGVKAVISKSFERIHRSNLVGMGIIPLCFKAGEDAETLGLTGQELYTIELPNNVSEIKPGQDVTVVTNNGKSFTCTLRFDTEVELAYFDHGGILQYVIRNLIKQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MASENPFRS
------CCCCCHHHH		26.0822223895
25PhosphorylationDGGEFGNYYSLPALN
CCCCCCCCCCCCCCC		8.5328295753
26PhosphorylationGGEFGNYYSLPALND
CCCCCCCCCCCCCCC		14.0228295753
27PhosphorylationGEFGNYYSLPALNDP
CCCCCCCCCCCCCCC		19.9528295753
108SulfoxidationLACMRDAMNNLGGDS
HHHHHHHHHHCCCCC		3.9123289948
147SulfoxidationENAVQANMELEFQRN
CCHHHHHHEEEEHHC		7.5323289948
178PhosphorylationMLVVPPGSGIVHQVN
CEEECCCCCCEEEEC		30.9928011693
335PhosphorylationGRSDDTVSMIEAYLR
CCCCCHHHHHHHHHH		19.0123776212
336SulfoxidationRSDDTVSMIEAYLRA
CCCCHHHHHHHHHHH		2.5223289948
346SulfoxidationAYLRANKMFVDYSEP
HHHHHCCCCCCCCCC		3.8723289948
656SulfoxidationEPPYFKGMTMSPPGP
CCCCCCCCCCCCCCC		2.6825693801
658SulfoxidationPYFKGMTMSPPGPHG
CCCCCCCCCCCCCCC		4.1525693801
659PhosphorylationYFKGMTMSPPGPHGV
CCCCCCCCCCCCCCC		20.8323111157
712PhosphorylationVDRRDFNSYGSRRGN
CCHHHCCCCCCCCCC		30.7529654922
713PhosphorylationDRRDFNSYGSRRGND
CHHHCCCCCCCCCCC		21.8925561503
715PhosphorylationRDFNSYGSRRGNDEI
HHCCCCCCCCCCCCH		15.5730407730
762SulfoxidationLSVFDAAMKYRNEGR
CCHHHHHHHHHCCCC		4.1425693801
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ACO1_ARATH !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ACO1_ARATH !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ACO1_ARATH !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ACO1_ARATH !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ACO1_ARATH

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Related Literatures of Post-Translational Modification

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