ACBP1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ACBP1_ARATH
• UniProt AC: Q9SM23
• Protein Name: Acyl-CoA-binding domain-containing protein 1
• Gene Name: ACBP1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 338
• Subcellular Localization: Cell membrane; Single-pass membrane protein. Secreted, cell wall. Endoplasmic reticulum membrane; Single-pass membrane protein. Detected in the cell walls of the outer integument cells at the seed coat.
• Protein Description: Binds medium- and long-chain acyl-CoA esters with very high affinity. Can interact in vitro with arachidonyl-CoA, barely with oleoyl-CoA, but not with palmitoyl-CoA. Confers tolerance and binds to lead ions Pb(2+), probably by promoting lead translocation from roots to shoots. May function as an intracellular carrier of acyl-CoA esters (By similarity)..
• Protein Sequence: MADWYQLAQSIIFGLIFAYLLAKLISILLAFKDENLSLTRNHTTQSEYENLRKVETLTGISGETDSLIAEQGSLRGDEDESDDDDWEGVESTELDEAFSAATAFVAAAASDRLSQKVSNELQLQLYGLYKIATEGPCTAPQPSALKMTARAKWQAWQKLGAMPPEEAMEKYIDLVTQLYPAWVEGGSKRRNRSGEAAGPMGPVFSSLVYEEESDNELKIDAIHAFAREGEVENLLKCIENGIPVNARDSEGRTPLHWAIDRGHLNVAEALVDKNADVNAKDNEGQTSLHYAVVCEREALAEFLVKQKADTTIKDEDGNSPLDLCESEWSWMREKKDSN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
35	N-linked_Glycosylation	LLAFKDENLSLTRNH HHHHCCCCCCCCCCC	45.09	-
41	N-linked_Glycosylation	ENLSLTRNHTTQSEY CCCCCCCCCCCHHHH	31.46	-
81	Phosphorylation	LRGDEDESDDDDWEG CCCCCCCCCCCCCCC	59.67	27531888
143	Phosphorylation	PCTAPQPSALKMTAR CCCCCCCCHHHHHHH	40.77	24894044
148	Phosphorylation	QPSALKMTARAKWQA CCCHHHHHHHHHHHH	16.05	24894044
191	N-linked_Glycosylation	EGGSKRRNRSGEAAG CCCCCCCCCCCCCCC	46.64	-
193	Phosphorylation	GSKRRNRSGEAAGPM CCCCCCCCCCCCCCC	44.53	27288362
209	Phosphorylation	PVFSSLVYEEESDNE HHHHHCCEECCCCCC	23.94	30407730
213	Phosphorylation	SLVYEEESDNELKID HCCEECCCCCCEEHH	49.36	27531888
249	Phosphorylation	IPVNARDSEGRTPLH CCCCCCCCCCCCCCE	36.08	25561503
253	Phosphorylation	ARDSEGRTPLHWAID CCCCCCCCCCEEEEC	40.85	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ACBP1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ACBP1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ACBP1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PLDA1_ARATH	PLDALPHA1	physical	23448237

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.