ABLM1_MOUSE - dbPTM
ABLM1_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ABLM1_MOUSE
UniProt AC Q8K4G5
Protein Name Actin-binding LIM protein 1
Gene Name Ablim1
Organism Mus musculus (Mouse).
Sequence Length 861
Subcellular Localization Cytoplasm . Cytoplasm, cytoskeleton . In a striped pattern along the myofibril axis in cardiac myocytes. Associated with the cytoskeleton.
Protein Description May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance..
Protein Sequence MPSLLGLKCLGKLCSSEIGKVPSPERASLRNSHRRLLIEDLSVPETPDPAHRRRGTVIHLVYLYSAGCGPPELRFSSYDPSVAHPQDPHHSSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGSPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPPNIPRSSSDFFYPKSLIRRTGRSPALQLLSPPCLTNSNKNPRQPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYEDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPELLSPGVHRWSPLRTSSFSSTHSDSRPNPPFRHHFLPHVKGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQSKASEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAVGTDPRRRSSGREEDEEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERASLASRYDSPLHSASHAPSSKTSSLPGYGKNGLHRPVSTDFAQYNSYGDISGGVRDYQTLPDGHMPAVRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKKKAKLF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2 (in isoform 5)Phosphorylation-33.4123375375
3 (in isoform 5)Phosphorylation-34.6223375375
214PhosphorylationQLCAQPMSSSPKEAS
HHHCCCCCCCCCCCC		34.0523737553
215PhosphorylationLCAQPMSSSPKEASC
HHCCCCCCCCCCCCC		44.3925521595
216PhosphorylationCAQPMSSSPKEASCS
HCCCCCCCCCCCCCC		32.4625521595
223PhosphorylationSPKEASCSSNCAGCG
CCCCCCCCCCCCCCC		23.3021082442
270PhosphorylationEYISKDGSPYCEKDY
EEECCCCCCCCCCCC		23.8816220185
273 (in isoform 2)Phosphorylation-6.2626239621
273 (in isoform 4)Phosphorylation-6.2626239621
275 (in isoform 2)Phosphorylation-59.1726643407
275 (in isoform 4)Phosphorylation-59.1726643407
276 (in isoform 2)Phosphorylation-20.7726239621
276 (in isoform 4)Phosphorylation-20.7726239621
277 (in isoform 2)Phosphorylation-18.6226643407
277 (in isoform 4)Phosphorylation-18.6226643407
279 (in isoform 2)Phosphorylation-19.4226643407
279 (in isoform 4)Phosphorylation-19.4226643407
281 (in isoform 2)Phosphorylation-15.7227717184
281 (in isoform 4)Phosphorylation-15.7227717184
282 (in isoform 2)Phosphorylation-24.0226643407
282 (in isoform 4)Phosphorylation-24.0226643407
286 (in isoform 2)Phosphorylation-48.9229899451
286 (in isoform 4)Phosphorylation-48.9229899451
287 (in isoform 2)Phosphorylation-12.9321183079
287 (in isoform 4)Phosphorylation-12.9321183079
291 (in isoform 2)Phosphorylation-2.1025338131
291 (in isoform 4)Phosphorylation-2.1025338131
319PhosphorylationSRCNQMFTEGEEMYL
CHHHCCCCCCCCEEE		37.4230635358
325PhosphorylationFTEGEEMYLQGSTVW
CCCCCCEEECCCEEE		10.1130635358
329PhosphorylationEEMYLQGSTVWHPDC
CCEEECCCEEECCCC		13.5630635358
330PhosphorylationEMYLQGSTVWHPDCK
CEEECCCEEECCCCC		34.1430635358
339PhosphorylationWHPDCKQSTKTEEKL
ECCCCCCCCCCHHHH		19.8430635358
340PhosphorylationHPDCKQSTKTEEKLR
CCCCCCCCCCHHHHC		39.2230635358
356PhosphorylationPNIPRSSSDFFYPKS
CCCCCCCCCCCCCHH		39.4223737553
390 (in isoform 2)Phosphorylation-65.5829514104
390 (in isoform 4)Phosphorylation-65.5829514104
391 (in isoform 2)Phosphorylation-45.0029899451
391 (in isoform 4)Phosphorylation-45.0029899451
395PhosphorylationNPRQPTRTSSESIYS
CCCCCCCCCCCCCCC		38.8025521595
395 (in isoform 2)Phosphorylation-38.8029899451
395 (in isoform 4)Phosphorylation-38.8029899451
396PhosphorylationPRQPTRTSSESIYSR
CCCCCCCCCCCCCCC		28.9027742792
397PhosphorylationRQPTRTSSESIYSRP
CCCCCCCCCCCCCCC		34.4521930439
397 (in isoform 2)Phosphorylation-34.4527742792
397 (in isoform 4)Phosphorylation-34.4527742792
399PhosphorylationPTRTSSESIYSRPGS
CCCCCCCCCCCCCCC		28.8627742792
401PhosphorylationRTSSESIYSRPGSSI
CCCCCCCCCCCCCCC		14.1227742792
402PhosphorylationTSSESIYSRPGSSIP
CCCCCCCCCCCCCCC		30.2627742792
406PhosphorylationSIYSRPGSSIPGSPG
CCCCCCCCCCCCCCC		27.9822499769
407PhosphorylationIYSRPGSSIPGSPGH
CCCCCCCCCCCCCCC		38.4222499769
409 (in isoform 2)Phosphorylation-38.8727742792
409 (in isoform 4)Phosphorylation-38.8727742792
410 (in isoform 2)Phosphorylation-44.8127742792
410 (in isoform 4)Phosphorylation-44.8127742792
411PhosphorylationPGSSIPGSPGHTIYA
CCCCCCCCCCCEEEE		23.5026824392
414 (in isoform 2)Phosphorylation-16.6921183079
414 (in isoform 4)Phosphorylation-16.6921183079
415PhosphorylationIPGSPGHTIYAKVDN
CCCCCCCEEEEEECC		22.9225521595
417PhosphorylationGSPGHTIYAKVDNEI
CCCCCEEEEEECCCC		11.0922499769
418 (in isoform 2)Phosphorylation-11.1021183079
418 (in isoform 4)Phosphorylation-11.1021183079
426 (in isoform 2)Phosphorylation-54.8421183079
426 (in isoform 4)Phosphorylation-54.8421183079
427PhosphorylationVDNEILDYKDLAAIP
ECCCCCCHHHHHCCC		11.7122817900
429 (in isoform 2)Phosphorylation-35.0021183079
429 (in isoform 4)Phosphorylation-35.0021183079
440PhosphorylationIPKVKAIYDIERPDL
CCCCEEEECCCCCCC		18.7422817900
449PhosphorylationIERPDLITYEPFYTS
CCCCCCEEECCCCCC		29.18-
454PhosphorylationLITYEPFYTSGYEDK
CEEECCCCCCCCCCH		15.6521183079
455PhosphorylationITYEPFYTSGYEDKQ
EEECCCCCCCCCCHH		18.9621183079
456PhosphorylationTYEPFYTSGYEDKQE
EECCCCCCCCCCHHH		28.1821183079
458PhosphorylationEPFYTSGYEDKQERQ
CCCCCCCCCCHHHHH		22.2621183079
466PhosphorylationEDKQERQSLGESPRT
CCHHHHHHCCCCCCC		44.5625521595
470PhosphorylationERQSLGESPRTLSPT
HHHHCCCCCCCCCCC		20.2025521595
473PhosphorylationSLGESPRTLSPTPSA
HCCCCCCCCCCCCCC		34.6625521595
475PhosphorylationGESPRTLSPTPSAEG
CCCCCCCCCCCCCCC		26.5618388127
477PhosphorylationSPRTLSPTPSAEGYQ
CCCCCCCCCCCCCCH		26.8824925903
479PhosphorylationRTLSPTPSAEGYQDV
CCCCCCCCCCCCHHH		41.2425521595
483PhosphorylationPTPSAEGYQDVRDRM
CCCCCCCCHHHHHHC		7.9529005
494PhosphorylationRDRMIHRSTSQGSIN
HHHCCCCCCCCCCCC		20.4624925903
495PhosphorylationDRMIHRSTSQGSINS
HHCCCCCCCCCCCCC		25.6525521595
496O-linked_GlycosylationRMIHRSTSQGSINSP
HCCCCCCCCCCCCCC		33.5221540332
496PhosphorylationRMIHRSTSQGSINSP
HCCCCCCCCCCCCCC		33.5224925903
499O-linked_GlycosylationHRSTSQGSINSPVYS
CCCCCCCCCCCCCCC		15.8021540332
499PhosphorylationHRSTSQGSINSPVYS
CCCCCCCCCCCCCCC		15.8025521595
502PhosphorylationTSQGSINSPVYSRHS
CCCCCCCCCCCCCCC		17.6725521595
505PhosphorylationGSINSPVYSRHSYTP
CCCCCCCCCCCCCCC		11.9022499769
506PhosphorylationSINSPVYSRHSYTPT
CCCCCCCCCCCCCCC		24.6122324799
509PhosphorylationSPVYSRHSYTPTTSR
CCCCCCCCCCCCCCC		29.5927180971
510PhosphorylationPVYSRHSYTPTTSRS
CCCCCCCCCCCCCCC		15.6029899451
511PhosphorylationVYSRHSYTPTTSRSP
CCCCCCCCCCCCCCC		19.7127742792
513PhosphorylationSRHSYTPTTSRSPQH
CCCCCCCCCCCCCCC		29.6021183079
514PhosphorylationRHSYTPTTSRSPQHF
CCCCCCCCCCCCCCC		24.2827742792
515PhosphorylationHSYTPTTSRSPQHFH
CCCCCCCCCCCCCCC		32.9927742792
517PhosphorylationYTPTTSRSPQHFHRP
CCCCCCCCCCCCCCH		28.7827742792
523DimethylationRSPQHFHRPELLSPG
CCCCCCCCHHHCCCC		25.99-
528PhosphorylationFHRPELLSPGVHRWS
CCCHHHCCCCCCCCC		32.0327742792
539PhosphorylationHRWSPLRTSSFSSTH
CCCCCCCCCCCCCCC		36.0827742792
540PhosphorylationRWSPLRTSSFSSTHS
CCCCCCCCCCCCCCC		23.9727742792
541PhosphorylationWSPLRTSSFSSTHSD
CCCCCCCCCCCCCCC		28.6527742792
543PhosphorylationPLRTSSFSSTHSDSR
CCCCCCCCCCCCCCC		35.9527742792
544PhosphorylationLRTSSFSSTHSDSRP
CCCCCCCCCCCCCCC		28.2927742792
545PhosphorylationRTSSFSSTHSDSRPN
CCCCCCCCCCCCCCC		24.9727742792
547PhosphorylationSSFSSTHSDSRPNPP
CCCCCCCCCCCCCCC		37.0527742792
549PhosphorylationFSSTHSDSRPNPPFR
CCCCCCCCCCCCCCC		53.2927742792
556DimethylationSRPNPPFRHHFLPHV
CCCCCCCCCCCCCCC		28.30-
570PhosphorylationVKGNEPSSGRNSPLP
CCCCCCCCCCCCCCC		53.1127742792
574PhosphorylationEPSSGRNSPLPYRPD
CCCCCCCCCCCCCCC		26.8423737553
578PhosphorylationGRNSPLPYRPDSRPL
CCCCCCCCCCCCCCC		42.3223737553
582PhosphorylationPLPYRPDSRPLTPTY
CCCCCCCCCCCCCCC		38.1823737553
586PhosphorylationRPDSRPLTPTYAQAP
CCCCCCCCCCCCCCC		19.1023737553
588PhosphorylationDSRPLTPTYAQAPKH
CCCCCCCCCCCCCCC		26.6723737553
589PhosphorylationSRPLTPTYAQAPKHF
CCCCCCCCCCCCCCC		9.6423737553
606PhosphorylationPDQGINIYRKPPIYK
CCCCCCEECCCCHHH		14.22105677
658PhosphorylationDHWPGPPSLAAVGTD
CCCCCCCCCCCCCCC		33.5027180971
670PhosphorylationGTDPRRRSSGREEDE
CCCCCCCCCCCCCCH		35.0225521595
671PhosphorylationTDPRRRSSGREEDEE
CCCCCCCCCCCCCHH		39.8125521595
696PhosphorylationEQLMKLNSGLGQLIL
HHHHHHHHHHHHHHH		45.9227180971
716PhosphorylationKESRERASLASRYDS
HHHHHHHHHHHHCCC		30.5929899451
721PhosphorylationRASLASRYDSPLHSA
HHHHHHHCCCCCCCC		20.488206597
723PhosphorylationSLASRYDSPLHSASH
HHHHHCCCCCCCCCC		22.0427742792
727PhosphorylationRYDSPLHSASHAPSS
HCCCCCCCCCCCCCC		38.8722817900
729PhosphorylationDSPLHSASHAPSSKT
CCCCCCCCCCCCCCC		24.1721454597
733PhosphorylationHSASHAPSSKTSSLP
CCCCCCCCCCCCCCC		45.2925338131
734O-linked_GlycosylationSASHAPSSKTSSLPG
CCCCCCCCCCCCCCC		38.6036012643
734PhosphorylationSASHAPSSKTSSLPG
CCCCCCCCCCCCCCC		38.6019367708
736PhosphorylationSHAPSSKTSSLPGYG
CCCCCCCCCCCCCCC		26.0428833060
737PhosphorylationHAPSSKTSSLPGYGK
CCCCCCCCCCCCCCC		33.3528833060
738PhosphorylationAPSSKTSSLPGYGKN
CCCCCCCCCCCCCCC		43.7625521595
742PhosphorylationKTSSLPGYGKNGLHR
CCCCCCCCCCCCCCC		24.0027149854
752PhosphorylationNGLHRPVSTDFAQYN
CCCCCCCCCCHHHHC		25.5827180971
753PhosphorylationGLHRPVSTDFAQYNS
CCCCCCCCCHHHHCC		35.0621082442
758PhosphorylationVSTDFAQYNSYGDIS
CCCCHHHHCCCCCCC		11.5728285833
760PhosphorylationTDFAQYNSYGDISGG
CCHHHHCCCCCCCCC		26.0927087446
761PhosphorylationDFAQYNSYGDISGGV
CHHHHCCCCCCCCCC		18.3875079
765PhosphorylationYNSYGDISGGVRDYQ
HCCCCCCCCCCCCCC		33.9528066266
771PhosphorylationISGGVRDYQTLPDGH
CCCCCCCCCCCCCCC		7.8829514104
773PhosphorylationGGVRDYQTLPDGHMP
CCCCCCCCCCCCCCC		33.7529514104
789PhosphorylationVRMDRGVSMPNMLEP
EECCCCCCCCCCCCC		31.2025521595
856AcetylationWRRNDMKKKAKLF--
HHCCHHHHHHHCC--		51.867632073
857AcetylationRRNDMKKKAKLF---
HCCHHHHHHHCC---		45.287632087
859AcetylationNDMKKKAKLF-----
CHHHHHHHCC-----		60.347632101
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ABLM1_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ABLM1_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ABLM1_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ABLM1_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ABLM1_MOUSE

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Large-scale phosphorylation analysis of mouse liver.";
Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-397; SER-411 ANDSER-496, AND MASS SPECTROMETRY.
"Qualitative and quantitative analyses of protein phosphorylation innaive and stimulated mouse synaptosomal preparations.";
Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F.,Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D.,Gerrits B., Panse C., Schlapbach R., Mansuy I.M.;
Mol. Cell. Proteomics 6:283-293(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-216; SER-475 ANDSER-502, AND MASS SPECTROMETRY.
"Specific phosphopeptide enrichment with immobilized titanium ionaffinity chromatography adsorbent for phosphoproteome analysis.";
Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.;
J. Proteome Res. 7:3957-3967(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-475 AND SER-494, ANDMASS SPECTROMETRY.
"Comprehensive identification of phosphorylation sites in postsynapticdensity preparations.";
Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R.,Burlingame A.L.;
Mol. Cell. Proteomics 5:914-922(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-475 AND SER-671, ANDMASS SPECTROMETRY.
"Proteomic analysis of in vivo phosphorylated synaptic proteins.";
Collins M.O., Yu L., Coba M.P., Husi H., Campuzano I.,Blackstock W.P., Choudhary J.S., Grant S.G.;
J. Biol. Chem. 280:5972-5982(2005).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-475, AND MASSSPECTROMETRY.
"Phosphoproteomic analysis of the developing mouse brain.";
Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., Gygi S.P.;
Mol. Cell. Proteomics 3:1093-1101(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-475 AND SER-479, ANDMASS SPECTROMETRY.
"Large-scale identification and evolution indexing of tyrosinephosphorylation sites from murine brain.";
Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.;
J. Proteome Res. 7:311-318(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-440, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory