dbPTM

ABIL2_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ABIL2_ARATH
UniProt AC	Q9M3A3
Protein Name	Protein ABIL2
Gene Name	ABIL2
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	312
Subcellular Localization	Cytoplasm, cytoskeleton.
Protein Description	Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex (By similarity)..
Protein Sequence	MPASHEASNYDEVSMQQSMLFSDGLQDLKNLRAQLYSAAEYFELSYTTDDKKQIVVETLKDYAVKALVNTVDHLGSVTYKVNDFIDEKVDEVSETELRVSCIEQRLRMCQEYMDHEGRSQQSLVIDTPKFHKRYILPAGEIMTATNLEKLKYFGSSLEDADDWNQFRNAVRATIRETPPPPVRKSTSQSSSPRQPPQRSATFSFTSTIPKKEQDKRSVSPHRFPLLRSGSVATRKSASISRPTTPSKSRSITPIRYPSEPRRSASVRVAFEKDNQKETEQQQPSKSKRLLKALLSRRKTKKDDTLYTFLDEY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
219	Phosphorylation	EQDKRSVSPHRFPLL HHCCCCCCCCCCCCC	19.08	19376835
250	Phosphorylation	TTPSKSRSITPIRYP CCCCCCCCCCCCCCC	37.59	25561503
252	Phosphorylation	PSKSRSITPIRYPSE CCCCCCCCCCCCCCC	17.57	25561503
256	Phosphorylation	RSITPIRYPSEPRRS CCCCCCCCCCCCCCC	16.30	25561503
258	Phosphorylation	ITPIRYPSEPRRSAS CCCCCCCCCCCCCCE	51.83	30407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ABIL2_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ABIL2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ABIL2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ABIL2_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ABIL2_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-219, AND MASSSPECTROMETRY.	19376835 [Abstract]