ABCA6_MOUSE - dbPTM
ABCA6_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ABCA6_MOUSE
UniProt AC Q8K441
Protein Name ATP-binding cassette sub-family A member 6
Gene Name Abca6
Organism Mus musculus (Mouse).
Sequence Length 1624
Subcellular Localization Membrane
Multi-pass membrane protein .
Protein Description Probable transporter which may play a role in macrophage lipid homeostasis..
Protein Sequence MKELSVHVRQQTRALLHKILLKKWRRKRESLLEWSIPIIIGLHMGLFSYLARNIQVLEVPPQDLGSLNEFNGSSLVVVYTPISNITQQIMNKTTFAPTMKGTRIIGVPSIEDLDEVLLHNIPDALGVIFNDSFSYQLKVLRMYGNPFLKEDLLAHCWDTHSQAFCSLSKYWERGFVALQTAINAGIIEVTTNHSVMEELMSIDGINMKTLPFIPRDLSDYEIFILFCLLYFSSFIYFASSNVTKERKQCKEVMKVMGLQDSAFWLSWGLIYVGFIFIISIFIAIIITSTQIIMMTGFLVIFTLFFLYGLSLIAVTFLMAVLLQKAVLTNLIVLFFTLFWGCVGFTVLHKELPPSLEWVLSIFSPFAFTSGMAKVIFQDYNLNGVVFPDPSGESYVMIAVFFILAFDSLLYLVLALYFDKILLYGAEHRSAPLFFLNPTSCFRKTANRNKVIERDLDPELPSDEYFEPVDPEYQGKEAIRIRNIKKEYKGKSGKVKALKGLFLDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDLKEIRKAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILSELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFSRQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGALKCTGSSVFLKRKWGLGYHLSLFMDETCDSERLTSFINHHIPYAKLKAKTKEKLVYILPLERTSEFPEFFSDLDKYSGQGLMSYEVSMSTLNDVFLNLEGEPSTKQDFEKRETATDSESLNDMEVAYPSLSQVQETVSTMSLWRMQVCAIARLRILKLKRERKAFLIILLLLGIALLPLVIEYVANALLEVKNNWEFKTDLYFLSPGQLPQGLRTSLLVINNTESNIEDFLQSLKHQNIVLEVDDFENRNATNSLSYNGAIIVSGRQKDYRFSAVCNTKRLHCFPILMNVISNGILHMLNHTQYIRIKEDIFSPFIVLVWTGIQETCLFILCVICSLSPHIAMSSVSDYKKKADSQLWISGLYPSAYWCGQAVVDISLFSGMLLTSYFTSYTSKLLNIDMTSEIVFSVIVLALGCAASLVFLTYVISFVFGKRKKNSTLWSICFLLVIAITFEKVANGPFNEALVISATMLVPSFALNGLLVVLEMRAYQYYIEFEEIKHGLSAVDLLLCLIPYIHTLLFIFVLRCLELKYGKNVVRRDPIFRIAPQSLKAQPNPEEPIDEDENVQAERLRTSDALSTPNLDEKPVIIASCLHKEYAGQKKHCCSRRTRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELKRLSSAVGHQGDSRAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAVVAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPVLILDEPSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVSGRLRCIGPIQHLKRKFGQDYVLELRVKDVSQEPLVHREILKLFPQAARQDRCFSLLTYKLPVTDVHPLSQAFHKLEAVKHGFDLEDYSLSQCTLDRVILELSKEQELGTVYEEADMTLGRKLLPPSDEL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
84N-linked_GlycosylationVVYTPISNITQQIMN
EEEEECCHHHHHHHC		41.88-
91N-linked_GlycosylationNITQQIMNKTTFAPT
HHHHHHHCCCCCCCC		39.90-
100UbiquitinationTTFAPTMKGTRIIGV
CCCCCCCCCCEEECC		60.6627667366
230PhosphorylationFILFCLLYFSSFIYF
HHHHHHHHHHHHHHH		6.6226239621
232PhosphorylationLFCLLYFSSFIYFAS
HHHHHHHHHHHHHHC		15.6926239621
233PhosphorylationFCLLYFSSFIYFASS
HHHHHHHHHHHHHCC		13.0326239621
236PhosphorylationLYFSSFIYFASSNVT
HHHHHHHHHHCCCCC		7.3526239621
239PhosphorylationSSFIYFASSNVTKER
HHHHHHHCCCCCHHH		16.7326239621
240PhosphorylationSFIYFASSNVTKERK
HHHHHHCCCCCHHHH		31.7126239621
429PhosphorylationLYGAEHRSAPLFFLN
HHCCCCCCCCEEEEC		35.8230352176
440S-palmitoylationFFLNPTSCFRKTANR
EEECHHHHHHHHCCC		4.1528526873
461PhosphorylationDLDPELPSDEYFEPV
CCCCCCCCCCCCCCC		56.5523984901
464PhosphorylationPELPSDEYFEPVDPE
CCCCCCCCCCCCCHH		20.4523984901
472PhosphorylationFEPVDPEYQGKEAIR
CCCCCHHHCCHHHHE		28.1429472430
552AcetylationLSDMQDLKEIRKAIG
HHHHHHHHHHHHHHC		60.4222902405
552UbiquitinationLSDMQDLKEIRKAIG
HHHHHHHHHHHHHHC		60.4222790023
556UbiquitinationQDLKEIRKAIGVCPQ
HHHHHHHHHHCCCCC		50.4422790023
561S-palmitoylationIRKAIGVCPQHNVQF
HHHHHCCCCCCCCEE		1.9528526873
576N-linked_GlycosylationDALTVKENLTLFAKI
EEEEECCCHHHHHHH		32.38-
582UbiquitinationENLTLFAKIKGILPQ
CCHHHHHHHCCCCCC		37.3022790023
658UbiquitinationQRIWGFLKERRADHV
HHHHHHHHHHCCCEE		47.0822790023
683UbiquitinationADILADRKVLIANGA
HHHHHCCCEEEECCC		41.7722790023
743UbiquitinationLKAKTKEKLVYILPL
HCCCCCCCEEEEEEC		44.8222790023
803PhosphorylationQDFEKRETATDSESL
HHHHHCCCCCCCCHH		38.6029472430
805PhosphorylationFEKRETATDSESLND
HHHCCCCCCCCHHHH		47.6929472430
807PhosphorylationKRETATDSESLNDME
HCCCCCCCCHHHHHH		25.4051457237
809PhosphorylationETATDSESLNDMEVA
CCCCCCCHHHHHHHH		36.1029472430
817PhosphorylationLNDMEVAYPSLSQVQ
HHHHHHHCCCHHHHH		9.8723984901
819PhosphorylationDMEVAYPSLSQVQET
HHHHHCCCHHHHHHH		28.1623984901
821PhosphorylationEVAYPSLSQVQETVS
HHHCCCHHHHHHHHH		32.4223984901
826PhosphorylationSLSQVQETVSTMSLW
CHHHHHHHHHHHHHH		11.5823984901
828PhosphorylationSQVQETVSTMSLWRM
HHHHHHHHHHHHHHH		26.3023984901
829PhosphorylationQVQETVSTMSLWRMQ
HHHHHHHHHHHHHHH		13.3723984901
838S-palmitoylationSLWRMQVCAIARLRI
HHHHHHHHHHHHHHH		0.9628526873
966S-palmitoylationDYRFSAVCNTKRLHC
CCCEEEEECCCCCCH		5.5328526873
1240UbiquitinationRIAPQSLKAQPNPEE
EECCCCCCCCCCCCC		50.6622790023
1274UbiquitinationSTPNLDEKPVIIASC
CCCCCCCCCEEEEEC		44.2322790023
1281S-palmitoylationKPVIIASCLHKEYAG
CCEEEEECCCHHHCC		3.2228526873
1298PhosphorylationKHCCSRRTRNMAVRN
CCCCCHHHHCCCCCC		25.8651457221
1307PhosphorylationNMAVRNVSFCVNKGE
CCCCCCEEEEEECCC		19.2429472430
1338UbiquitinationRMIAGITKPTAGQVE
HHHCCCCCCCCCCEE		38.1522790023
1347UbiquitinationTAGQVELKRLSSAVG
CCCCEEHHHHHHHCC		37.4727667366
1350PhosphorylationQVELKRLSSAVGHQG
CEEHHHHHHHCCCCC		21.9330352176
1351PhosphorylationVELKRLSSAVGHQGD
EEHHHHHHHCCCCCC		31.4029472430
1366S-palmitoylationSRAEFGYCPQENGLW
CCCCCEECCCCCCCC		2.6128526873
1467UbiquitinationQAIQAVVKDNEKGVL
HHHHHHHCCCCCCEE		48.5122790023
1536UbiquitinationLVHREILKLFPQAAR
CCCHHHHHHCHHHHH		54.4622790023
1587S-palmitoylationEDYSLSQCTLDRVIL
CCCCCCCCCHHHHHH		3.5228526873
1597PhosphorylationDRVILELSKEQELGT
HHHHHHHHHCCCCCC		25.4430482847
1616UbiquitinationADMTLGRKLLPPSDE
HCCCCCCCCCCCCCC		53.2122790023
1621PhosphorylationGRKLLPPSDEL----
CCCCCCCCCCC----		41.6030352176
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ABCA6_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ABCA6_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ABCA6_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of ABCA6_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ABCA6_MOUSE

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Related Literatures of Post-Translational Modification

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