ABC1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ABC1_SCHPO
• UniProt AC: Q92337
• Protein Name: ATP-binding cassette transporter abc1
• Gene Name: abc1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 1427
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MKMFQSFFSNYIDINFFRNATLDQCLLLFYLSLFSLTNLFLIQKLFHANHTQHPLKKYFGETCLLEYIQIILSIVSAALSFYLDTNAVWWAIRTITHLEIVGLNILSSLKYGSTLFSWISVANAFGLLLLRLISIYDFLTYSSWSFSVKGGSFLLLLPLAYNITLFLLVIIPLFFPRAWSPTVKFSKVARPSPEQTCSIFSLIFTYGWLNGIIWKSWKKPITLTDVPALPDTECTQIWYSRFAKNDRKSLMHTILLSLKSTILLMVFLSVLVSSTLFVTPLAIKKLLQYLQNPKSDEGNSPFLWVFVLLIGPYLASVVKELYVHVSRRFMLRIKAAITQMIYKKVLTSKTLFVAVDGSKINLDYVYNLLAKDVDNIGEMREFIGIIARAPLEMGVSMYFLYQLLGWSAYVGLLLAILSSSFPLLVASKISRLTSIANTSSDERIRLTTELLKSIKITKLFGWERPMLSRIQEKRSFEVNNMYSLTLFDIIFKSGMKIAPFISMFITFAIYTKIMGHQLTPATAFTSISMFGLLRYQFIWLASVSRQFIQFKVSLKRVDNFVYGNMVNDSSIESSDSFVFENTSLSWSPTPSTALFQLKNLNFTIPRNQFTLVVGSTGSGKSTLAMALLGELHVISGKMTTPSISQRIAYVPQAAWLRNGTIRSNILFGEPYDEERYFQIIKACCLDSDLNSMNDGDLTYIHSNGSSLSGGQKQRVSLARALYSNAEVYIFDDIFSALDVSTSRKIYESCFLSTLLQHKTIILFTHNVSLCLPIAENVIVLKNSTAQLVSPDSIQELVPSTFFSSNTKKDNIEEENLEPHSFSFDSTLASSSDNDEQRDFASNSSIVLLGLHYLKYFGSNKYILGSILLVMMSQVSLASIHFWIALWSGNSLFSLKLPSSFSFLWGYAILLFIYFLMDLSRAITFAKGGRTASENIHDILSERVLYSPLHWFEKTAAGRILNRFSKDMYATDNLLWASLEGMLLCVMAILITMLNVTLVMPIFMVPAAFVSLLVYLHGYAYSKAQKQLTSLQSSRTSPVFTMLGETLGGITVIRAFKKEKIFEHENMAFIDDMIQPLYISFAINRWLAIRTDGISGLVGFSTGLIALLRQNIPPGLVGFSLNSAIGFNISVLVFVRANNEILTYINNFRRLYEYMLLPSEKNESSCLTKPMNKEWPTLGHVSIKNLTVSYSIGQAAVLEDINLEILPKEKIAIVGRTGSGKSTMGLTLLRFTMIMSGAVEVDGIDINSLDLEVLRQRISLIPQDPVLISGTVRSNLDPFEEYGDGELNEILKTASCESLVQASNKNSLDAFAIHLDTPVDSGGVNFSSGQRQILALARALVRKSRIVILDESTASVDDTTDRRIQQMLRAAFKHATVLCIAHRIKTIVDYDKVLVLDSGKTVEFGSPKSLYTQRRAFWKMCKESHISL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
49	N-linked_Glycosylation	IQKLFHANHTQHPLK HHHHHCCCCCCCCHH	30.12	-
437	N-linked_Glycosylation	SRLTSIANTSSDERI HHHHHHCCCCHHHHH	38.53	-
567	N-linked_Glycosylation	FVYGNMVNDSSIESS EEECCCCCCCCCCCC	32.45	-
581	N-linked_Glycosylation	SDSFVFENTSLSWSP CCCEEEECCCCCCCC	24.41	-
601	N-linked_Glycosylation	LFQLKNLNFTIPRNQ EEEEECCCEEEECCE	41.21	-
658	N-linked_Glycosylation	PQAAWLRNGTIRSNI CHHHHHCCCCCCCCC	50.19	-
703	N-linked_Glycosylation	DLTYIHSNGSSLSGG CCEEEECCCCCCCCC	39.96	-
782	N-linked_Glycosylation	ENVIVLKNSTAQLVS CCEEEEECCCCEECC	40.19	-
842	N-linked_Glycosylation	EQRDFASNSSIVLLG HHHHHHHCHHHHHHH	36.03	-
994	N-linked_Glycosylation	AILITMLNVTLVMPI HHHHHHHHHHHHHHH	17.57	-
1161	N-linked_Glycosylation	MLLPSEKNESSCLTK HCCCCCCCCCCCCCC	50.78	-
1184	N-linked_Glycosylation	LGHVSIKNLTVSYSI CCCCEEEEEEEEEEE	38.99	-
1324	N-linked_Glycosylation	PVDSGGVNFSSGQRQ CCCCCCCCCCHHHHH	34.06	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ABC1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ABC1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ABC1_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of ABC1_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.