dbPTM

ABAP1_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ABAP1_ARATH
UniProt AC	B7U179
Protein Name	ARMADILLO BTB ARABIDOPSIS PROTEIN 1
Gene Name	ABAP1
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	737
Subcellular Localization	Nucleus .
Protein Description	May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). In association with TCP24, exerts a negative role in cell proliferation in leaves, possibly by inhibiting mitotic DNA replication..
Protein Sequence	MIISKSFKAPLKFSVKSSTAPVISNHPPMENHPKRQRTTRLAARNLKRKLSHNTDGAPIVTQLIDIDDEPIDLVVAIRRHVEVLNSSFSDPDFDHEAVKEAAADIADLAKIDENVEIIVENGAIPALVRYLESPLVVCGNVPKSCEHKLEKDCALALGLIAAIQPGYQQLIVDAGAIVPTVKLLKRRGECGECMFANAVIRRAADIITNIAHDNPRIKTNIRVEGGIAPLVELLNFPDVKVQRAAAGALRTVSFRNDENKSQIVELNALPTLVLMLQSQDSTVHGEAIGAIGNLVHSSPDIKKEVIRAGALQPVIGLLSSTCLETQREAALLIGQFAAPDSDCKVHIAQRGAITPLIKMLESSDEQVVEMSAFALGRLAQDAHNQAGIAHRGGIISLLNLLDVKTGSVQHNAAFALYGLADNEENVADFIKAGGIQKLQDDNFTVQPTRDCVVRTLKRLQNKIHGPVLNQLLYLMRTAEKTVQIRIALALAHLCDPKDGKLIFIDNNGVEFLLELLYFSSNKQQRYSSSALYELAKKATSFAPEDSAPCSPTQQVFLGEKFVNNPTMSDVTFLIDGKQFYAHKIGLVASSDIFRAMFDGLYKERNAQNVEIPNIRWEVFELMMKFIYSGRINIAKHLAKDLLVAADQYLLEGLKRQCEYTIAQEICLDNIPEMYELADTFNASALRRACTLFVLEHFTKLSSQLWFAKFVKQIIPEIRSYMTDILTRPVEASPPTVV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
527	Phosphorylation	SNKQQRYSSSALYEL CCCCCCCCHHHHHHH	21.72	19880383
532	Phosphorylation	RYSSSALYELAKKAT CCCHHHHHHHHHHHH	14.49	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ABAP1_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ABAP1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ABAP1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CDT1A_ARATH	CDT1A	physical	18818695
CDT1B_ARATH	CDT1B	physical	18818695
TCP24_ARATH	TCP24	physical	18818695

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ABAP1_ARATH

Related Literatures of Post-Translational Modification