AB12B_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AB12B_ARATH
• UniProt AC: Q9FWX8
• Protein Name: ABC transporter B family member 12
• Gene Name: ABCB12
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1273
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MNRDGAGEGDSVSHEHSTSKTDEKAKTVPLYKLFAFADSFDVFLMICGSLGAIGNGVCLPLMTLLFGDLIDSFGKNQNNKDIVDVVSKVCLKFVYLGLGRLGAAFLQVACWMITGERQAAKIRSNYLKTILRQDIGFFDVETNTGEVVGRMSGDTVHIQDAMGEKVGKFIQLVSTFVGGFALAFAKGWLLTLVMLTSIPFLAMAGAAMALLVTRASSRGQAAYAKAATVVEQTIGSIRTVASFTGEKQAINSYKKYITSAYKSSIQQGFSTGLGLGVMIYVFFSSYALAIWFGGKMILEKGYTGGSVINVIIIVVAGSMSLGQTSPCVTAFAAGQAAAYKMFETIKRKPLIDAYDVNGKVLGDIRGDIELKDVHFSYPARPDEEIFDGFSLFIPSGATAALVGESGSGKSTVINLIERFYDPKAGEVLIDGINLKEFQLKWIRSKIGLVCQEPVLFSSSIMENIAYGKENATLQEIKVATELANAAKFINNLPQGLDTKVGEHGTQLSGGQKQRIAIARAILKDPRVLLLDEATSALDTESERVVQEALDRVMVNRTTVVVAHRLSTVRNADMIAVIHSGKMVEKGSHSELLKDSVGAYSQLIRCQEINKGHDAKPSDMASGSSFRNSNLNISREGSVISGGTSSFGNSSRHHSLNVLGLFAGLDLGSGSQRVGQEETGTTSQEPLRKVSLTRIAALNKPEIPVLLLGTVVAAINGAIFPLFGILISRVIEAFFKPADQLKKDSRFWAIIFVALGVTSLIVSPSQMYLFAVAGGKLIRRIQSMCFEKAVHMEVSWFDEPENSSGTMGARLSTDAALIRALVGDALSLAVQNAASAASGLIIAFTASWELALIILVMLPLIGINGFLQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQMYNKQCEGPIKDGVKQGFISGLGFGFSFFILFCVYATSFYAAARLVEDGKTTFIDVFQVFFALTMAAIGISQSSTFAPDSSKAKVAAASIFAIIDRKSKIDSSDETGTVLENVKGDIELRHLSFTYPARPGIQIFRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGQITLDGVELKKLQLKWLRQQMGLVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKFISSIQQGYDTVVGEKGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERLVQDALDRVIVNRTTVVVAHRLSTIKNADVIAIVKNGVIAENGTHETLIKIDGGVYASLVQLHMTASN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
470	N-linked_Glycosylation	NIAYGKENATLQEIK HHHCCCCCCCHHHHH	41.53	-
555	N-linked_Glycosylation	ALDRVMVNRTTVVVA HHHHHCCCCCEEEEE	19.93	-
587	Phosphorylation	GKMVEKGSHSELLKD CCEEECCCHHHHHHH	34.60	19880383
631	N-linked_Glycosylation	SFRNSNLNISREGSV CCCCCCCCCCCCCCE	34.15	-
648	N-linked_Glycosylation	GGTSSFGNSSRHHSL CCCCCCCCCCCCCCC	34.50	-
801	N-linked_Glycosylation	SWFDEPENSSGTMGA ECCCCCCCCCCCCCC	52.79	-
1116	N-linked_Glycosylation	GQEPVLFNDTIRANI CCCCCCCCCEEHHHE	41.16	-
1217	N-linked_Glycosylation	ALDRVIVNRTTVVVA HHHHHHCCCCEEEEE	25.18	-
1247	N-linked_Glycosylation	KNGVIAENGTHETLI ECCEECCCCCCCEEE	52.20	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AB12B_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AB12B_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AB12B_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of AB12B_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.