AAT5_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AAT5_ARATH
• UniProt AC: P46248
• Protein Name: Aspartate aminotransferase, chloroplastic
• Gene Name: ASP5
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 453
• Subcellular Localization: Plastid, chloroplast. Plastid, amyloplast .
• Protein Description: Amino acid aminotransferase important for the metabolism of amino acids and Krebs-cycle related organic acids. No activity with D-Asp or D-Ala as amino donors. In plants, it is involved in nitrogen metabolism and in aspects of carbon and energy metabolism..
• Protein Sequence: MASLMLSLGSTSLLPREINKDKLKLGTSASNPFLKAKSFSRVTMTVAVKPSRFEGITMAPPDPILGVSEAFKADTNGMKLNLGVGAYRTEELQPYVLNVVKKAENLMLERGDNKEYLPIEGLAAFNKATAELLFGAGHPVIKEQRVATIQGLSGTGSLRLAAALIERYFPGAKVVISSPTWGNHKNIFNDAKVPWSEYRYYDPKTIGLDFEGMIADIKEAPEGSFILLHGCAHNPTGIDPTPEQWVKIADVIQEKNHIPFFDVAYQGFASGSLDEDAASVRLFAERGMEFFVAQSYSKNLGLYAERIGAINVVCSSADAATRVKSQLKRIARPMYSNPPVHGARIVANVVGDVTMFSEWKAEMEMMAGRIKTVRQELYDSLVSKDKSGKDWSFILKQIGMFSFTGLNKAQSDNMTDKWHVYMTKDGRISLAGLSLAKCEYLADAIIDSYHNVS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
107	Sulfoxidation	VKKAENLMLERGDNK HHHHHHHEECCCCCC	5.72	25693801
177	Phosphorylation	PGAKVVISSPTWGNH CCCEEEEECCCCCCC	20.75	22092075
298	N6-(pyridoxal phosphate)lysine	FVAQSYSKNLGLYAE EEEEEHHHCCCCHHH	48.21	-
298	Other	FVAQSYSKNLGLYAE EEEEEHHHCCCCHHH	48.21	-
316	Phosphorylation	AINVVCSSADAATRV CEEEEECCHHHHHHH	25.66	22092075
380	Phosphorylation	VRQELYDSLVSKDKS HHHHHHHHHHCCCCC	19.67	25561503
383	Phosphorylation	ELYDSLVSKDKSGKD HHHHHHHCCCCCCCC	40.19	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AAT5_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AAT5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AAT5_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of AAT5_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.