dbPTM

AASD1_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	AASD1_RAT
UniProt AC	Q5XI97
Protein Name	Alanyl-tRNA editing protein Aarsd1
Gene Name	Aarsd1
Organism	Rattus norvegicus (Rat).
Sequence Length	412
Subcellular Localization	Cytoplasm.
Protein Description	Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala)..
Protein Sequence	MAFLCQRDSYAREFTTTVVSCCPAELQTDGNGSKKEVLSGFQVVLEDTLLFPEGGGQPDDRGTINDISVLRVTRRGAQADHFTQTPLSPGSQVQVRVDWERRFDHMQQHSGQHLITAVADLLFGLKTTSWELGKLRCVIELDSPSVTAEQVAAIEQSVNQKIRDRLPVSVRELSLDDPEVEQVRGRGLPDDHAGPIRVVTIEGVDSNMCCGTHVNNLSDLQVIKILGTEKGKKNKSNLIFLAGNRVLKWMERSHGSEKALTSLLKCGAEDHVEAVKKLQNATKLLQKNNLNLLRDLAVHTAHTLRSSPAWGGVVTLHRKEGDSEFMNIIANEIGSEETLLFLTVGDEKGAGLFLLAGPTEAVETLGPRVAEVLEGKGAGKKGRFQGKATKMSRRAEVQALLQDYVSTQSAEE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
83	Phosphorylation	GAQADHFTQTPLSPG CCCCCEEECCCCCCC	28.28	27097102
85	Phosphorylation	QADHFTQTPLSPGSQ CCCEEECCCCCCCCE	24.12	27097102
88	Phosphorylation	HFTQTPLSPGSQVQV EEECCCCCCCCEEEE	28.55	28689409
91	Phosphorylation	QTPLSPGSQVQVRVD CCCCCCCCEEEEEEE	30.48	27097102
174	Phosphorylation	PVSVRELSLDDPEVE CCCEEEECCCCHHHH	25.62	28432305
376	Ubiquitination	VAEVLEGKGAGKKGR HHHHHCCCCCCCCCC	35.89	-
404	Phosphorylation	VQALLQDYVSTQSAE HHHHHHHHHHHCCCC	5.37	27097102
406	Phosphorylation	ALLQDYVSTQSAEE- HHHHHHHHHCCCCC-	17.94	27097102
407	Phosphorylation	LLQDYVSTQSAEE-- HHHHHHHHCCCCC--	19.25	27097102
409	Phosphorylation	QDYVSTQSAEE---- HHHHHHCCCCC----	37.42	27097102

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of AASD1_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of AASD1_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of AASD1_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of AASD1_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of AASD1_RAT

Related Literatures of Post-Translational Modification