| UniProt ID | AAAS_MOUSE | |
|---|---|---|
| UniProt AC | P58742 | |
| Protein Name | Aladin | |
| Gene Name | Aaas | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 546 | |
| Subcellular Localization | Nucleus, nuclear pore complex. | |
| Protein Description | Plays a role in the normal development of the peripheral and central nervous system.. | |
| Protein Sequence | MCSLGLFPPPPPRGQVTLYEHNNELVTGNSYESPPPDFRGQWINLPVLHLTKDPLKAPGRLDHGTRTAFIHHREQVWKRCINVWHDVGLFGVLNEIANSEEEVFEWVKTACSWALALCGRASSLHGSLFPHLSLRSEDLIAEFAQVTNWSSCCLRVFAWHPHTNKFAVALLDDSIRVYNANSTIVPSLKHRLQRNVAALAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPNGGWLLSASPVDAVILVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKVLATTPSAVFRVWEAQMWTCEAWPTLSGRCQTGCWSPDGNRLLFTVLGEALIYSLSFPERCGTGKGHVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGNPQVQDGNPVILLFRTRNSPVFELLPCGIIQGEPGAQAQLITFHPSFNKGALLSVCWSTGRITHIPLYFVNAQFPRFSPVLGRAQEPPAGGGGSIHEVPLFTETSPTSAPWDPLPGQSSAQPHSPHSHL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MCSLGLFPP ------CCCCCCCCC | 4.65 | - | |
| 33 | Phosphorylation | VTGNSYESPPPDFRG ECCCCCCCCCCCCCC | 34.18 | - | |
| 56 | Malonylation | HLTKDPLKAPGRLDH EECCCCCCCCCCCCC | 58.90 | 26320211 | |
| 133 | Phosphorylation | GSLFPHLSLRSEDLI CCCCCCCCCCCHHHH | 20.78 | 22942356 | |
| 480 | Phosphorylation | CWSTGRITHIPLYFV HHCCCCCCEEEEEEE | 16.64 | 22345495 | |
| 485 | Phosphorylation | RITHIPLYFVNAQFP CCCEEEEEEECCCCC | 10.50 | 22345495 | |
| 495 | Phosphorylation | NAQFPRFSPVLGRAQ CCCCCCCCCCCCCCC | 18.51 | 26824392 | |
| 511 | Phosphorylation | PPAGGGGSIHEVPLF CCCCCCCCCCEEECC | 24.85 | 25159016 | |
| 519 | Phosphorylation | IHEVPLFTETSPTSA CCEEECCCCCCCCCC | 46.14 | 25367039 | |
| 521 | Phosphorylation | EVPLFTETSPTSAPW EEECCCCCCCCCCCC | 36.63 | 25293948 | |
| 522 | Phosphorylation | VPLFTETSPTSAPWD EECCCCCCCCCCCCC | 21.68 | 25159016 | |
| 524 | Phosphorylation | LFTETSPTSAPWDPL CCCCCCCCCCCCCCC | 36.97 | 25159016 | |
| 525 | Phosphorylation | FTETSPTSAPWDPLP CCCCCCCCCCCCCCC | 35.40 | 25159016 | |
| 535 | Phosphorylation | WDPLPGQSSAQPHSP CCCCCCCCCCCCCCC | 33.29 | 9419137 | |
| 536 | Phosphorylation | DPLPGQSSAQPHSPH CCCCCCCCCCCCCCC | 24.04 | 25159016 | |
| 541 | Phosphorylation | QSSAQPHSPHSHL-- CCCCCCCCCCCCC-- | 30.87 | 22942356 | |
| 544 | Phosphorylation | AQPHSPHSHL----- CCCCCCCCCC----- | 29.84 | 25159016 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of AAAS_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of AAAS_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of AAAS_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of AAAS_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "Large scale localization of protein phosphorylation by use ofelectron capture dissociation mass spectrometry."; Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.; Mol. Cell. Proteomics 8:904-912(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-495, AND MASSSPECTROMETRY. | |
