A16L2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: A16L2_MOUSE
• UniProt AC: Q6KAU8
• Protein Name: Autophagy-related protein 16-2
• Gene Name: Atg16l2
• Organism: Mus musculus (Mouse).
• Sequence Length: 623
• Subcellular Localization: Cytoplasm. Localizes also to discrete punctae along the ciliary axoneme.
• Protein Description: May play a role in autophagy..
• Protein Sequence: MAGPGAPCDPCAPAAVWKRHIVRQLRHRDRTQKALFLELVPAYNHLLEKAELLAKFSEKLKSEPKDAISTRHEDWREEVSGTGPDQVSSPASLRVKWQQEKKGLQLVCGEMAYQVVKKSAALDTLQSQLEERQDRLEALQACVVQLQEARAQQSRQLEERQAENAAQREAYETLLQQAVHQEAALRRLQEEARDLLEQLVQRKARAAAERNLRNERRERANQALVSQELKKAAKRTVSISEIPNTLEDGTKEETVALAPAALPEFSESETCEKWKRPFRSASATSLTLSRCVDVVKGLLDFKKRRGHSVGGAPEQRYQSIPVCVSAQIPSQAQDVLDAHLSEVNAVCFGPNSSLLATGGADRLIHLWNVVGGRLEANQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQLWKVGETQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCIQVIPVQGRVTSLHLSYDQLHLLSCSRDNTLKVIDLRISNIRQVFRADGFKCSSDWTKAVFSPDRSYALAGSSNGDLYIWDVNTGKLETSLQGPHCTAVNAVAWCFSGNHVVSVDQGRKVVLWH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
70	Phosphorylation	EPKDAISTRHEDWRE CCCCHHHCCCHHHHH	29.90	28059163
88	Phosphorylation	GTGPDQVSSPASLRV CCCCCCCCCCCHHEE	25.60	28066266
89	Phosphorylation	TGPDQVSSPASLRVK CCCCCCCCCCHHEEE	26.15	28066266
92	Phosphorylation	DQVSSPASLRVKWQQ CCCCCCCHHEEEEHH	21.79	28066266
154	Phosphorylation	QEARAQQSRQLEERQ HHHHHHHHHHHHHHH	15.20	22802335
236	Phosphorylation	LKKAAKRTVSISEIP HHHHHHCCCCHHHCC	20.21	28066266
238	Phosphorylation	KAAKRTVSISEIPNT HHHHCCCCHHHCCCC	21.56	28066266
240	Phosphorylation	AKRTVSISEIPNTLE HHCCCCHHHCCCCCC	23.20	28066266
280	Phosphorylation	KWKRPFRSASATSLT HCCCCCCCCCCHHHC	27.27	28833060
282	Phosphorylation	KRPFRSASATSLTLS CCCCCCCCCHHHCHH	33.07	22942356
284	Phosphorylation	PFRSASATSLTLSRC CCCCCCCHHHCHHHH	23.05	28833060
285	Phosphorylation	FRSASATSLTLSRCV CCCCCCHHHCHHHHH	21.05	28833060
287	Phosphorylation	SASATSLTLSRCVDV CCCCHHHCHHHHHHH	23.58	28833060
308	Phosphorylation	FKKRRGHSVGGAPEQ HHHHCCCCCCCCCHH	25.86	25521595
538	Phosphorylation	KVIDLRISNIRQVFR EEEEEEECCHHHHHH	21.55	24719451
571	Phosphorylation	RSYALAGSSNGDLYI CCCEECCCCCCCEEE	18.28	-
572	Phosphorylation	SYALAGSSNGDLYIW CCEECCCCCCCEEEE	43.87	-
577	Phosphorylation	GSSNGDLYIWDVNTG CCCCCCEEEEECCCC	12.52	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of A16L2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of A16L2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of A16L2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of A16L2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.