4CLLA_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: 4CLLA_ARATH
• UniProt AC: Q9SMT7
• Protein Name: Oxalate--CoA ligase {ECO:0000305}
• Gene Name: AAE3 {ECO:0000303|PubMed:22447686}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 514
• Subcellular Localization: Cytoplasm .
• Protein Description: Oxalyl-CoA synthetase acting exclusively against oxalate. No activity with malonate, succinate, malate, acetate, formate, lactate, glycolate, glyoxylate or glutarate. Required for oxalate degradation, normal seed development and defense against oxalate-producing fungal pathogens..
• Protein Sequence: MDSDTLSGLLENVAKKFPDRRALSVSGKFNLTHARLHDLIERAASRLVSDAGIKPGDVVALTFPNTVEFVIMFLAVIRARATAAPLNAAYTAEEFEFYLSDSDSKLLLTSKEGNAPAQEAASKLKISHVTATLLDAGSDLVLSVADSDSVVDSATELVNHPDDGALFLHTSGTTSRPKGVPLTQLNLASSVKNIKAVYKLTESDSTVIVLPLFHVHGLLAGLLSSLGAGAAVTLPAAGRFSATTFWPDMKKYNATWYTAVPTIHQIILDRHASHPETEYPKLRFIRSCSASLAPVILSRLEEAFGAPVLEAYAMTEATHLMSSNPLPEEGPHKPGSVGKPVGQEMAILNEKGEIQEPNNKGEVCIRGPNVTKGYKNNPEANKAGFEFGWFHTGDIGYFDTDGYLHLVGRIKELINRGGEKISPIEVDAVLLTHPDVSQGVAFGVPDEKYGEEINCAVIPREGTTVTEEDIKAFCKKNLAAFKVPKRVFITDNLPKTASGKIQRRIVAQHFLEKP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MDSDTLSG -------CCHHHHHH	11.40	22223895
3	Phosphorylation	-----MDSDTLSGLL -----CCHHHHHHHH	31.06	19880383
109	Phosphorylation	SDSKLLLTSKEGNAP CCCCEEEECCCCCCC	37.41	19880383
110	Phosphorylation	DSKLLLTSKEGNAPA CCCEEEECCCCCCCH	28.78	19880383
463	Phosphorylation	AVIPREGTTVTEEDI EEECCCCCCCCHHHH	17.22	22631563
464	Phosphorylation	VIPREGTTVTEEDIK EECCCCCCCCHHHHH	35.97	22631563
490	Phosphorylation	VPKRVFITDNLPKTA CCCEEEEECCCCCCC	13.84	24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of 4CLLA_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of 4CLLA_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of 4CLLA_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of 4CLLA_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.