| UniProt ID | 2ABA_ARATH | |
|---|---|---|
| UniProt AC | Q38821 | |
| Protein Name | Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform | |
| Gene Name | PP2AB1 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 513 | |
| Subcellular Localization | ||
| Protein Description | The B regulatory subunit may modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.. | |
| Protein Sequence | MNGGDEVVAASADPSLPLEWRFSQVFGERSAGEEVQEVDIISAIEFDNSGNHLATGDRGGRVVLFERTDTNNSSGTRRELEEADYPLRHPEFRYKTEFQSHDPEFDYLKSLEIEEKINKIRWCQTANGALFLLSTNDKTIKFWKVQDKKIKKICDMNSDPSRTVGNGTVASSSNSNITNSCLVNGGVSEVNNSLCNDFSLPAGGISSLRLPVVVTSHESSPVARCRRVYAHAHDYHINSISNNSDGETFISADDLRINLWNLEISNQSFNIVDVKPAKMEDLSEVITSAEFHPTHCNMLAYSSSKGSIRLIDLRQSALCDSHSKLFEEPEQAGPKSFFTEIIASVSDIKFAKEGRYLLSRDYMTLKLWDINMDAGPVATFQVHEYLKPKLCDLYENDSIFDKFECCISGNGLRAATGSYSNLFRVFGVAPGSTETATLEASRNPMRRHVPIPSRPSRALSSITRVVSRGSESPGVDGNTNALDYTTKLLHLAWHPNENSIACAAANSLYMYYA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MNGGDEVV -------CCCCCEEE | 10.70 | - | |
| 218 (in isoform 2) | Phosphorylation | - | 53.32 | 23111157 | |
| 219 | Phosphorylation | VVVTSHESSPVARCR EEEECCCCCHHHHHH | 34.22 | 25561503 | |
| 219 (in isoform 2) | Phosphorylation | - | 34.22 | 23111157 | |
| 220 | Phosphorylation | VVTSHESSPVARCRR EEECCCCCHHHHHHH | 22.02 | 23111157 | |
| 460 | Phosphorylation | SRPSRALSSITRVVS CCHHHHHHHHEEEHH | 20.79 | 30291188 | |
| 461 | Phosphorylation | RPSRALSSITRVVSR CHHHHHHHHEEEHHC | 28.91 | 23776212 | |
| 463 | Phosphorylation | SRALSSITRVVSRGS HHHHHHHEEEHHCCC | 21.25 | 23776212 | |
| 467 | Phosphorylation | SSITRVVSRGSESPG HHHEEEHHCCCCCCC | 28.24 | 30407730 | |
| 470 | Phosphorylation | TRVVSRGSESPGVDG EEEHHCCCCCCCCCC | 33.52 | 19880383 | |
| 472 | Phosphorylation | VVSRGSESPGVDGNT EHHCCCCCCCCCCCC | 28.75 | 19880383 | |
| 479 | Phosphorylation | SPGVDGNTNALDYTT CCCCCCCCCHHHHHH | 27.65 | 23776212 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of 2ABA_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of 2ABA_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of 2ABA_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of 2ABA_ARATH !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-460, AND MASSSPECTROMETRY. | |
