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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 3-isopropylmalate dehydratase small subunit 1

UniprotKB/SwissProt ID: Q9ZW85 (Q9ZW85)

Gene Name: SSU1

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (PubMed:19597944). Plays an essential role in leucine biosynthesis (PubMed:19597944, PubMed:20663849, PubMed:24608865, PubMed:32612621). Functions in both the biosynthesis of leucine, and in the methionine chain elongation pathway of aliphatic glucosinolate formation (PubMed:24608865). Plays an essential role in female gametophyte development (PubMed:19597944, PubMed:20663849, PubMed:24608865)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Plastid, chloroplast stroma. Plastid

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR015928 Aconitase/3IPM_dehydase_swvl
IPR000573 AconitaseA/IPMdHydase_ssu_swvl
IPR033940 IPMI_Swivel
IPR050075 LeuD

The S-nitrosylation sites of Q9ZW85

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 142 SIIIGGENFG C GSSREHAPVC   
2 152 CGSSREHAPV C LGAAGAKAVV   
3 190 VYPLDSEVRV C DECTTGDVAT