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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Peroxisomal fatty acid beta-oxidation multifunctional protein MFP2

UniprotKB/SwissProt ID: Q9ZPI5 (Q9ZPI5)

Gene Name: MFP2

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Involved in peroxisomal fatty acid beta-oxidation during seed germination. Possesses enoyl-CoA hydratase activity against long chain substrates (C14-C18) and 3-hydroxyacyl-CoA dehydrogenase activity against chains of variable sizes (C6-C18) (PubMed:10521521, PubMed:16507084, PubMed:20463021). Possesses 3-hydroxy-3-phenylpropionyl-CoA dehydrogenase activity and is involved in the peroxisomal beta-oxidation pathway for the biosynthesis of benzoic acid (BA). Required for the accumulation in seeds of substituted hydroxybenzoylated choline esters, which are BA-containing secondary metabolites (PubMed:24254312). Fatty acid beta-oxidation pathway in peroxisomes regulates gene silencing, histone acetylation and DNA methylation (PubMed:31064880)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Glyoxysome. Peroxisome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR006180 3-OHacyl-CoA_DH_CS
IPR006176 3-OHacyl-CoA_DH_NAD-bd
IPR006108 3HC_DH_C
IPR008927 6-PGluconate_DH-like_C_sf
IPR029045 ClpP/crotonase-like_dom_sf
IPR018376 Enoyl-CoA_hyd/isom_CS
IPR001753 Enoyl-CoA_hydra/iso
IPR036291 NAD(P)-bd_dom_sf