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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1

UniprotKB/SwissProt ID: Q9ZNT0 (Q9ZNT0)

Gene Name: SKD1

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Involved in the transport of biosynthetic membrane proteins from the prevacuolar/endosomal compartment to the vacuole. Required for multivesicular body (MVB) protein sorting. Catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes, such as the disassembly of the ESCRT-III complex (PubMed:17468262, PubMed:20663085, PubMed:21810997, PubMed:22258747, PubMed:24812106). May also regulate cell cycle (PubMed:20663085). Required during seed development for the formation of mucilage in seed coat and testa (PubMed:20930567). Involved in the maintenance of Na(+)/K(+) homeostasis under salt stress (PubMed:23580756). Required for cell expansion (PubMed:24385429)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Endosome, multivesicular body membrane. Prevacuolar compartment membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR003960 ATPase_AAA_CS
IPR007330 MIT_dom
IPR036181 MIT_dom_sf
IPR050304 MT-severing_AAA_ATPase
IPR027417 P-loop_NTPase
IPR015415 Spast_Vps4_C
IPR045253 VPS4_MIT

The S-nitrosylation sites of Q9ZNT0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 342 EGFSGSDVSV C VKDVLFEPVR