Protein Name:
Mitochondrial carnitine/acylcarnitine carrier protein
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UniprotKB/SwissProt ID: Q9Z2Z6 (Q9Z2Z6)
Gene Name:
Slc25a20
Organism: Mus musculus (Mouse)
Function: Mediates the electroneutral exchange of acylcarnitines (O-acyl-(R)-carnitine or L-acylcarnitine) of different acyl chain lengths (ranging from O-acetyl-(R)-carnitine to long-chain O-acyl-(R)-carnitines) with free carnitine ((R)-carnitine or L-carnitine) across the mitochondrial inner membrane, via a ping-pong mechanism. Key player in the mitochondrial oxidation pathway, it translocates the fatty acids in the form of acylcarnitines into the mitochondrial matrix, where the carnitine palmitoyltransferase 2 (CPT-2) activates them to undergo fatty acid beta-oxidation. Catalyzes the unidirectional transport (uniport) of carnitine at lower rates than the antiport (exchange)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion inner membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9Z2Z6
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
136 |
GIMTPGERIK C LLQIQASSGE |
CCCCCCCCCH H HHHHCCCCCC |
4.22% |
21278135
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| 2 |
155 |
GENKYSGTLD C AKKLYQEFGI |
CCCCCCCCCH H HHHHCCCCCC |
7.23% |
21278135
|
| 3 |
23 |
NLLAGGFGGM C LVFVGHPLDT |
CCCCCCCCCH H HHHHCCCCCC |
3.11% |
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| 4 |
283 |
MIRAFPANAA C FLGFEIAMKF |
CCCCCCCCCH H HHHHCCCCCC |
2.41% |
21278135
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| 5 |
58 |
QPPMYSGTLD C FRKTLMREGI |
CCCCCCCCCH H HHHHCCCCCC |
3.9% |
21278135
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| 6 |
89 |
IIGVTPMFAV C FFGFGLGKKL |
CCCCCCCCCH H HHHHCCCCCC |
1.78% |
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