Protein Name:
Mitochondrial proton/calcium exchanger protein
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UniprotKB/SwissProt ID: Q9Z2I0 (Q9Z2I0)
Gene Name:
Letm1
Organism: Mus musculus (Mouse)
Function: Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport (PubMed:23716663, PubMed:27669901). Mediates proton-dependent calcium efflux from mitochondrion (PubMed:23716663, PubMed:27669901). Functions also as an electroneutral mitochondrial proton/potassium exchanger (By similarity). Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain (By similarity). Required for the maintenance of the tubular shape and cristae organization (By similarity). Essential for early embryonic development (PubMed:23716663)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion inner membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9Z2I0
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
329 |
NLTRPQLVAL C KLLELQSIGT |
CCHHHHHHCC C CCCCCCCCCC |
1.79% |
21278135
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