Protein Name:
Potassium-transporting ATPase alpha chain 2
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UniprotKB/SwissProt ID: Q9Z1W8 (Q9Z1W8)
Gene Name:
Atp12a
Organism: Mus musculus (Mouse)
Function: The catalytic subunit of a H(+)/K(+) ATPase and/or Na(+)/K(+) ATPase pump which transports K(+) ions in exchange for Na(+) and/or H(+) ions across the apical membrane of epithelial cells. Uses ATP as an energy source to pump K(+) ions into the cell while transporting Na(+) and/or H(+) ions to the extracellular compartment (By similarity). Involved in the maintenance of electrolyte homeostasis through K(+) ion absorption in kidney and colon (PubMed:9449685). In the airway epithelium, may play a primary role in mucus acidification regulating its viscosity and clearance (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Apical cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9Z1W8
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
367 |
LTAKRMAKKN C LVKNLEAVET |
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| 2 |
617 |
RSTVPDAVSK C RSAGIKVIMV |
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| 3 |
716 |
PQQKLIIVEG C QRQDAVVAVT |
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