Protein Name:
Chloride intracellular channel protein 1
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UniprotKB/SwissProt ID: Q9Z1Q5 (Q9Z1Q5)
Gene Name:
Clic1
Organism: Mus musculus (Mouse)
Function: In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Reduces selenite and dehydroascorbate and may act as an antioxidant during oxidative stress response (By similarity). Can insert into membranes and form voltage-dependent multi-ion conductive channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Involved in regulation of the cell cycle (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Nucleus membrane. Cytoplasm. Cell membrane. Endoplasmic reticulum
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9Z1Q5
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
178 |
LDGNELTLAD C NLLPKLHIVQ |
CCCCCCCEEE E EEECCCCCEE |
3% |
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| 2 |
191 |
LPKLHIVQVV C KKYRGFTIPE |
CCCCCCCEEE E EEECCCCCEE |
3.1% |
21278135
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| 3 |
223 |
AYAREEFAST C PDDEEIELAY |
CCCCCCCEEE E EEECCCCCEE |
3.01% |
21278135
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| 4 |
24 |
AGSDGAKIGN C PFSQRLFMVL |
CCCCCCCEEE E EEECCCCCEE |
2.8% |
21278135
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| 5 |
59 |
KRRTETVQKL C PGGQLPFLLY |
CCCCCCCEEE E EEECCCCCEE |
3.66% |
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