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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Voltage-dependent calcium channel subunit alpha-2/delta-3

UniprotKB/SwissProt ID: Q9Z1L5 (Q9Z1L5)

Gene Name: Cacna2d3

Organism: Mus musculus (Mouse)

Function: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) but not T-type (CACNA1G)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR051173 Ca_channel_alpha-2/delta
IPR013680 VDCC_a2/dsu
IPR013608 VWA_N
IPR002035 VWF_A
IPR036465 vWFA_dom_sf

The S-nitrosylation sites of Q9Z1L5

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 969 AQKLKQTLEP C DTEYPAFVSE