Protein Name:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
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UniprotKB/SwissProt ID: Q9Z1B3 (Q9Z1B3)
Gene Name:
Plcb1
Organism: Mus musculus (Mouse)
Function: Catalyzes the hydrolysis of 1-phosphatidylinositol 4,5-bisphosphate into diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) and mediates intracellular signaling downstream of G protein-coupled receptors (PubMed:27653213). Regulates the function of the endothelial barrier (PubMed:27653213)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus membrane. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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