Protein Name:
Anion exchange protein 2
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UniprotKB/SwissProt ID: Q9Z0S8 (Q9Z0S8)
Gene Name:
SLC4A2
Organism: Cavia porcellus (Guinea pig)
Function: Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane (By similarity). Plays an important role in osteoclast differentiation and function (By similarity). Regulates bone resorption and calpain-dependent actin cytoskeleton organization in osteoclasts via anion exchange-dependent control of pH (By similarity). Essential for intracellular pH regulation in CD8(+) T-cells upon CD3 stimulation, modulating CD8(+) T-cell response (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Apical cell membrane. Basolateral cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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