UniprotKB/SwissProt ID: Q9Z0S5 (Q9Z0S5)
Gene Name:
Cldn15
Organism: Mus musculus (Mouse)
Function: Forms paracellular channels: polymerizes in tight junction strands with cation- and water-selective channels through the strands, conveying epithelial permeability in a process known as paracellular tight junction permeability (PubMed:18242218, PubMed:20727355, PubMed:23089202, PubMed:37100833). In intestinal epithelium, allows for sodium and water fluxes from the peritoneal side to the lumen of the intestine to regulate nutrient absorption and intestinal morphogenesis (PubMed:18242218, PubMed:20727355, PubMed:23089202, PubMed:37100833)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell junction, tight junction. Cell membrane
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