UniprotKB/SwissProt ID: Q9Y6Y9 (Q9Y6Y9)
Gene Name:
LY96
Organism: Homo sapiens (Human)
Function: Binds bacterial lipopolysaccharide (LPS) (PubMed:17569869, PubMed:17803912). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria (PubMed:11160242, PubMed:11593030). Enhances TLR4-dependent activation of NF-kappa-B (PubMed:10359581). Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10359581)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted, extracellular space. Secreted
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