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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Actin-binding protein WASF2

UniprotKB/SwissProt ID: Q9Y6W5 (Q9Y6W5)

Gene Name: WASF2

Organism: Homo sapiens (Human)

Function: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Basolateral cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR028288 SCAR/WAVE_fam
IPR003124 WH2_dom

The S-nitrosylation sites of Q9Y6W5

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 127 PVPVLETYNT C DTPPPLNNLT   
2 27 TLPSVRSELE C VTNITLANVI