Protein Name:
Nuclear receptor coactivator 3
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UniprotKB/SwissProt ID: Q9Y6Q9 (Q9Y6Q9)
Gene Name:
NCOA3
Organism: Homo sapiens (Human)
Function: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9Y6Q9
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
627 |
GHKKLLQLLT C SSDDRGHSSL |
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| 2 |
716 |
TGKDTSSITS C GDGNVVKQEQ |
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| 3 |
769 |
VEGVDNKMSQ C TSSTIPSSSQ |
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