Protein Name:
Suppressor of tumorigenicity 14 protein
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UniprotKB/SwissProt ID: Q9Y5Y6 (Q9Y5Y6)
Gene Name:
ST14
Organism: Homo sapiens (Human)
Function: Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site (PubMed:10373424). Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing (PubMed:18843291). Proteolytically cleaves and therefore activates TMPRSS13 (PubMed:28710277)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane
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Graphical Visualization of S-nitrosylation Sites:
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