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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Mannose-1-phosphate guanylyltransferase catalytic subunit beta

UniprotKB/SwissProt ID: Q9Y5P6 (Q9Y5P6)

Gene Name: GMPPB

Organism: Homo sapiens (Human)

Function: Catalytic subunit of the GMPPA-GMPPB mannose-1-phosphate guanylyltransferase complex (PubMed:33986552). Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids (PubMed:33986552). Can catalyze the reverse reaction in vitro (PubMed:33986552). Together with GMPPA regulates GDP-alpha-D-mannose levels (PubMed:33986552)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR056729 GMPPB_C
IPR045233 GMPPB_N
IPR018357 Hexapep_transf_CS
IPR050486 Mannose-1P_guanyltransferase
IPR005835 NTP_transferase_dom
IPR029044 Nucleotide-diphossugar_trans

The S-nitrosylation sites of Q9Y5P6

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 149 EEPSKYGVVV C EADTGRIHRF   
2 245 SLRQKQPERL C SGPGIVGNVL