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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Mitochondrial import inner membrane translocase subunit Tim22

UniprotKB/SwissProt ID: Q9Y584 (Q9Y584)

Gene Name: TIMM22

Organism: Homo sapiens (Human)

Function: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion inner membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR039175 TIM22

The S-nitrosylation sites of Q9Y584

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 69 QKMIEKAMES C AFKAALACVG