Protein Name:
Hypoxia up-regulated protein 1
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UniprotKB/SwissProt ID: Q9Y4L1 (Q9Y4L1)
Gene Name:
HYOU1
Organism: Homo sapiens (Human)
Function: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. Promotes HSPA5/BiP-mediated ATP nucleotide exchange and thereby activates the unfolded protein response (UPR) pathway in the presence of endoplasmic reticulum stress (By similarity). May play a role as a molecular chaperone and participate in protein folding
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum lumen
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9Y4L1
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
352 |
KVTRVEFEEL C ADLFERVPGP |
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| 2 |
805 |
KEKLAELRKL C QGLFFRVEER |
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