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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Unconventional myosin-Va

UniprotKB/SwissProt ID: Q9Y4I1 (Q9Y4I1)

Gene Name: MYO5A

Organism: Homo sapiens (Human)

Function: Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Can hydrolyze ATP in the presence of actin, which is essential for its function as a motor protein (PubMed:10448864). Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane (By similarity). May also be required for some polarization process involved in dendrite formation (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002710 Dilute_dom
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR037988 Myo5a_CBD
IPR001609 Myosin_head_motor_dom-like
IPR004009 Myosin_N
IPR036103 MYSc_Myo5
IPR027417 P-loop_NTPase

The S-nitrosylation sites of Q9Y4I1

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1008 DLEQTRSEKK C IEEHADRYKQ