Protein Name:
Meiosis regulator and mRNA stability factor 1
|
UniprotKB/SwissProt ID: Q9Y4F3 (Q9Y4F3)
Gene Name:
MARF1
Organism: Homo sapiens (Human)
Function: Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Peroxisome
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
