\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Plexin-D1

UniprotKB/SwissProt ID: Q9Y4D7 (Q9Y4D7)

Gene Name: PLXND1

Organism: Homo sapiens (Human)

Function: Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature (By similarity). Mediates anti-angiogenic signaling in response to SEMA3E

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Cell projection, lamellipodium membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002909 IPT_dom
IPR031148 Plexin
IPR042719 Plexin-D1_Sema
IPR013548 Plexin_cytoplasmic_RasGAP_dom
IPR046800 Plexin_RBD
IPR002165 Plexin_repeat
IPR016201 PSI
IPR008936 Rho_GTPase_activation_prot
IPR001627 Semap_dom
IPR036352 Semap_dom_sf
IPR041019 TIG1_plexin
IPR015943 WD40/YVTN_repeat-like_dom_sf

The S-nitrosylation sites of Q9Y4D7

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1921 VALMEDNIYE C YSEA------   
2 430 DSVVQGTGPA C ERKLNIQLQP