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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Microtubule cross-linking factor 1

UniprotKB/SwissProt ID: Q9Y4B5 (Q9Y4B5)

Gene Name: MTCL1

Organism: Homo sapiens (Human)

Function: Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation (PubMed:23902687). Plays a role in the development and maintenance of non-centrosomal microtubule bundles at the lateral membrane in polarized epithelial cells (PubMed:23902687). Required for faithful chromosome segregation during mitosis (PubMed:33587225)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Lateral cell membrane. Apical cell membrane. Cytoplasm, cytoskeleton, spindle pole. Midbody. Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR049885 MTCL1-3
IPR027882 SOGA1/2-like_CC
IPR027881 SOGA_CC

The S-nitrosylation sites of Q9Y4B5

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 800 SGKPSEASEP C PTELLKARED