Protein Name:
Nucleolar complex protein 2 homolog
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UniprotKB/SwissProt ID: Q9Y3T9 (Q9Y3T9)
Gene Name:
NOC2L
Organism: Homo sapiens (Human)
Function: Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus, nucleoplasm. Nucleus, nucleolus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9Y3T9
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
567 |
FLRECKVANY C RQVQQLLGKV |
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| 2 |
585 |
GKVQENSAYI C SRRQRVSFGV |
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