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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Methionine-R-sulfoxide reductase B2, mitochondrial

UniprotKB/SwissProt ID: Q9Y3D2 (Q9Y3D2)

Gene Name: MSRB2

Organism: Homo sapiens (Human)

Function: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR028427 Met_Sox_Rdtase_MsrB
IPR002579 Met_Sox_Rdtase_MsrB_dom
IPR011057 Mss4-like_sf