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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Inner nuclear membrane protein Man1

UniprotKB/SwissProt ID: Q9Y2U8 (Q9Y2U8)

Gene Name: LEMD3

Organism: Homo sapiens (Human)

Function: Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus inner membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR052277 INM_ESCRT-Associated
IPR011015 LEM/LEM-like_dom_sf
IPR003887 LEM_dom
IPR018996 Man1/Src1-like_C
IPR034394 Man1_RRM
IPR041885 MAN1_winged_helix_dom
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf

The S-nitrosylation sites of Q9Y2U8

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 254 VNGSRLVPYS C RENYSDSEEE   
2 346 EAAAAEQGGG C DQVDSSPVPR   
3 754 VWRWIQPSAS C DKILVIPSKV   
4 833 IAVDKNSREG C VYVKCLSPEY