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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Polymerase delta-interacting protein 2

UniprotKB/SwissProt ID: Q9Y2S7 (Q9Y2S7)

Gene Name: POLDIP2

Organism: Homo sapiens (Human)

Function: Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites (PubMed:24191025). May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1) (PubMed:24191025, PubMed:26984527)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR007474 ApaG_domain
IPR036767 ApaG_sf
IPR011722 Hemimethylated_DNA-bd_dom
IPR036623 Hemimethylated_DNA-bd_sf

The S-nitrosylation sites of Q9Y2S7

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 143 YYQVLIDARD C PHISQRSQTE  CCCHHHHHHH H CCCCHHHCCC  1.89% 19483679