Protein Name:
Little elongation complex subunit 1
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UniprotKB/SwissProt ID: Q9Y2F5 (Q9Y2F5)
Gene Name:
ICE1
Organism: Homo sapiens (Human)
Function: Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies (PubMed:23932780)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Nucleus, Cajal body
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The S-nitrosylation sites of Q9Y2F5
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1817 |
VKTGSSSGGD C NQDKSRDLGT |
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| 2 |
2253 |
SKSVPSAIVS C LEEVSALSTE |
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