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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Little elongation complex subunit 1

UniprotKB/SwissProt ID: Q9Y2F5 (Q9Y2F5)

Gene Name: ICE1

Organism: Homo sapiens (Human)

Function: Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies (PubMed:23932780)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Nucleus, Cajal body

The S-nitrosylation sites of Q9Y2F5

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1817 VKTGSSSGGD C NQDKSRDLGT   
2 2253 SKSVPSAIVS C LEEVSALSTE