Protein Name:
Nck-associated protein 1
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UniprotKB/SwissProt ID: Q9Y2A7 (Q9Y2A7)
Gene Name:
NCKAP1
Organism: Homo sapiens (Human)
Function: Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Cell projection, lamellipodium membrane
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR019137
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Nck-associated_protein-1 |
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The S-nitrosylation sites of Q9Y2A7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
556 |
SRAFEKMFQQ C LELPSQSRYS |
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| 2 |
622 |
NLITDICTEQ C TLSDQLLPKH |
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| 3 |
969 |
YELSSAAGLP C EIDPALVVAL |
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