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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Non-selective voltage-gated ion channel VDAC3

UniprotKB/SwissProt ID: Q9Y277 (Q9Y277)

Gene Name: VDAC3

Organism: Homo sapiens (Human)

Function: Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane and plasma membrane (PubMed:31935282). Forms a high-conducting channel with a stable open state and a voltage-induced closure with a mild preference for anions over cations (PubMed:31935282). Involved in male fertility and sperm mitochondrial sheath formation (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion outer membrane. Membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR023614 Porin_dom_sf
IPR001925 Porin_Euk
IPR027246 Porin_Euk/Tom40

The S-nitrosylation sites of Q9Y277

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 2 ---------M C NTPTYCDLGK  CCCCCCCCCH H HHHHHHHHCC  8.58%
2 36 MVKIDLKTKS C SGVEFSTSGH  CCCCCCCCCH H HHHHHHHHCC  4.35%
3 65 SGNLETKYKV C NYGLTFTQKW  CCCCCCCCCH H HHHHHHHHCC  2.58% 20140087
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