Protein Name:
RNA-binding protein FXR2
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UniprotKB/SwissProt ID: Q9WVR4 (Q9WVR4)
Gene Name:
Fxr2
Organism: Mus musculus (Mouse)
Function: mRNA-binding protein that acts as a regulator of mRNAs translation and/or stability, and which is required for adult hippocampal neurogenesis (PubMed:21658585). Specifically binds to AU-rich elements (AREs) in the 3'-UTR of target mRNAs (PubMed:21658585). Promotes formation of some phase-separated membraneless compartment by undergoing liquid-liquid phase separation upon binding to AREs-containing mRNAs: mRNAs storage into membraneless compartments regulates their translation and/or stability (By similarity). Acts as a regulator of adult hippocampal neurogenesis by regulating translation and/or stability of NOG mRNA, thereby preventing NOG protein expression in the dentate gyrus (PubMed:21658585)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, Cytoplasmic ribonucleoprotein granule. Cytoplasm. Postsynapse
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Graphical Visualization of S-nitrosylation Sites:
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