\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Solute carrier family 12 member 7

UniprotKB/SwissProt ID: Q9WVL3 (Q9WVL3)

Gene Name: Slc12a7

Organism: Mus musculus (Mouse)

Function: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling (PubMed:11551954, PubMed:12106695). May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti (PubMed:11976689). May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (Probable)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR004841 AA-permease/SLC12A_dom
IPR000076 KCL_cotranspt
IPR018491 SLC12_C
IPR004842 SLC12A_fam