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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: MAGUK p55 subfamily member 2

UniprotKB/SwissProt ID: Q9WV34 (Q9WV34)

Gene Name: Mpp2

Organism: Mus musculus (Mouse)

Function: Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity). In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression (PubMed:26880549). Seems to negatively regulate SRC function in epithelial cells (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell projection, dendrite. Postsynaptic density. Cytoplasm, cytoskeleton. Membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR020590 Guanylate_kinase_CS
IPR014775 L27_C
IPR004172 L27_dom
IPR036892 L27_dom_sf
IPR050716 MAGUK
IPR035602 MPP2_SH3
IPR027417 P-loop_NTPase
IPR001478 PDZ
IPR036034 PDZ_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain

The S-nitrosylation sites of Q9WV34

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 310 LELTPTSGTL C GSLSGKKKKR  CCCCCCCCHH H HHHHHHHHCC  3.32% 24895380
16418269