Protein Name:
Sodium channel protein type 8 subunit alpha
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UniprotKB/SwissProt ID: Q9WTU3 (Q9WTU3)
Gene Name:
Scn8a
Organism: Mus musculus (Mouse)
Function: Pore-forming subunit of a voltage-gated sodium channel complex assuming opened or closed conformations in response to the voltage difference across membranes and through which sodium ions selectively pass along their electrochemical gradient. Contributes to neuronal excitability by regulating action potential threshold and propagation More specifically expressed in non-neuronal cells, could play a role in sodium release from intracellular compartments and participate in the control of podosomes formation and macrophages adhesion and movement
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Cell projection, axon. Cytoplasmic vesicle. Cell projection, podosome
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Graphical Visualization of S-nitrosylation Sites:
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