Protein Name:
Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial
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UniprotKB/SwissProt ID: Q9W265 (Q9W265)
Gene Name:
T3dh
Organism: Drosophila melanogaster (Fruit fly)
Function: Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2-KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion
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Graphical Visualization of S-nitrosylation Sites:
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